Medicinal Chemistry : An Introduction

Rating:
Summary: IT BRIMS WITH QUALITY 'ACTIVE INGREDIENTS'
Review: Accompanied by elaborated worked examples, as well as self-assessment questions, the components of this book are complete. It introduces its reader to the underlying principles of drugs discovery and development, using the simplest possible method. Each one of its illustrated chapters included content-summary at the end of that chapter.
From pharmaceutical chemistry to pharmacological kinetics, the introductory scope of this book is unique. Sound narrations regarding methods of Drug Discovery, Combinatorial Synthesis, Drug Action, Receptor Structure and Signal Transduction, as well as many others, gave this book a top niche in my scale of text preferences.
Its price is reasonable, and its pages are overflowing with pieces of hard-to-beat information. I will not hesitate to recommend this book for pharmacy students; and for any other person who takes introductory pharmacology course. It is very sound.

Rating:
Summary: great book, but lots of errors
Review: As an undergraduate text for medicinal chemistry, I think this book is the best in the market. It's appropriate for students who have only had two semesters of organic chemistry. The layout is logical. Aside from chapter 7 (chelating agents), the first nine chapters are at least decent and mostly very good. Chapter 10 (nucleic acids) and 11 (nitric oxide) probably belong more in a biochem text than a med chem book. Chapter 12 (organic synthesis) is well out of the scope of this book and falls flat.

The book has a huge number of errors. Most of which are in the chemical figures and will not bother anyone unless they like looking at structures. Some of the errors involve the mathematic equations and could cause trouble for a student who isn't paying attention.

The only major complaint I have about the book is that chapter 5 (pharmacokinetics) is almost completely devoid of units on the variables in the equations and graphs. Proper use of units would greatly help a student in learning material in this chapter.

While not perfect, this book is very good for a junior/senior upper-level chemistry course.