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Rating: Summary: Poorly Written, Good graphics Review: Every technician and/or PI should own a copy of this text for their lab. With the logical diagrams and full explanation of the text, this book is really condensed and assumes some knowledge of molecular biology. This book does not assume knowledge of genomics, but rather serves as a manual.
Rating: Summary: The future may view this text as a foundation for GS Review: Every technician and/or PI should own a copy of this text for their lab. With the logical diagrams and full explanation of the text, this book is really condensed and assumes some knowledge of molecular biology. This book does not assume knowledge of genomics, but rather serves as a manual.
Rating: Summary: Poorly Written, Good graphics Review: The book is very poorly written and is too difficult to follow to be called a "primer." Authors often focus on actual software tools and how to use them rather than the science behind them. To be fair, the graphics offered in the book are excellent and sometimes are the only way to understand a difficult concept. The preface says to be familiar with "the content of a typical 300 level undergraduate course in genetics" -- it should be a definite prerequisite for reading this book.
Rating: Summary: Excellent overview of Functional and Structural Genomics Review: This somewhat understated book may be overlooked based on its title, and yet it represents the best book currently in print to provide a solid overview of the science and issues in genome science, functional and structural genomics, and the subdiscipline proteomics. Chapter 1 describes current progress with mapping genomes, including the human genome and other genomes in plants and animals. Chapter 2 describes sequencing approaches and gene identification. Chapter 3 deals with gene expression and technologies. Chapter 4 focuses on proteomics including brief introductions to 2D-PAGE and mass spectrometry. This chapter also briefly introduces the reader to structural genomics, or the prediction of protein structure based on sequence through threading and modeling. After a chapter on single nucletide polymorphisms and genotyping the book concludes with a chapter on integrating genome studies including the use of in silico approaches. Although scant in detail in parts, a major strength of the book is the wide coverage given to science of genomics and its offshoots. Overall an excellent course text for undergraduate or early postgraduate students or others interested in these emerging disciplines. I am not aware of any competing texts which such coverage and certainly not at the price of this one.
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