Guide to Analysis of DNA Microarray Data, Second Edition

Rating:
Summary: Recommended Book
Review: "...I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Cell Biology Newsletter)

Rating:
Summary: Useful Book
Review: "...This useful little book .... I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Developmental Biology Newsletter)

Rating:
Summary: an easy read -- a cookbook
Review: This is the best short introduction that I've seen to DNA
microarray analysis - and our lab has just about every
computational biology book ever published. (We are the core
array analysis facility at the U of Colorado School of Medicine,
operating downstream of one of the largest single Affymetrix
facilities in academia.)
This book is clear, accurate, and concise - I'm very
enthusiastic about it. I've recommended it to everyone in
our lab, and to our collaborators. I have even xeroxed the
analysis flow chart in fig 2.1, annotated it a bit, and
taped it on our lab door. I found something I really liked
on just about every other page. One example: the comparison
between Euclidean and Pearson correlation distance on pp.
45-46 is the best short explanation I have ever seen.
Chapter 2 on basic data analysis is superb (it even manages
to describe the Multiple Testing problem in its limited
number of pages), and the chapters on investigating
regulatory nets and molecular classifiers give you a wonderful
taste of some cutting-edge stuff within their length constraints.
All the chapters are excellent. Biblio is very current. Price
is a little steep ... for ~150 pages, but it's a great
little book. 5 stars.

Rating:
Summary: an easy read -- a cookbook
Review: True to its stated purpose: best used as a roadmap by mathematically unsophisticated newcomers to analysis of microarray data. Somewhat superficial, and it becomes more so in later chapters. Does not explore harder issues in detail. Does not touch upon future directions of the technology. Its advocacy of the Unix awk program is anachronistic; tellingly, the reference cited for awk is from 1988. Not a groundbreaking book, just solid practical advice.