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Enough : Setting Limits on Human Genetic Technology

Enough : Setting Limits on Human Genetic Technology

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Rating: 5 stars
Summary: Enough's enough.
Review: As Wendell Berry has observed, this is not a happy book. It would be a mistake to dismiss Bill McKibben (THE END OF NATURE, 1989) as a Luddite for raising the question of whether recent technological advances will result in the disenchantment of human existence. ENOUGH is as much about ongoing advances in genetic engineering, nanotechnology, and robotics as it is about what it really means to be a human being. Just as Aldoux Huxley envisioned a dehumanized future in his 1932 science fiction classic, BRAVE NEW WORLD, McKibben offers his readers a compelling look into the future, and it is hell. He foresees a future in which, instead of making babies by making love, parents genetically engineer their babies in laboratories, and robots render humans obsolete. While he convincingly argues that we've reached an "enough point" (p. 118), where most aspects of our daily life could not be dramatically improved by new technology, and that we should instead be using technology to make quantum leaps in medicine to deal with illness, to aid the poor around the world, and to conquer death (p. 122), McKibben also makes it rather clear that there is very little we can do to escape the technological advances threatening to futher devalue human existence. It is still enough to read ENOUGH for the troubling questions it raises about the future of humanity.

G. Merritt

Rating: 5 stars
Summary: Something we all need to think about
Review: Bill McKibben's latest book, "Enough: Staying Human in an Engineered Age," raises some fundamental questions about who we are, what we are, and how we may be affected by the biotechnologies which we already possess and those which are just over the horizon. The author takes us on an expedition into the world of genetic research, nanotechnology and robotics.

This is a passionate book and a disturbing book and one that presents what we in the "argumentation trade" might call a "persuasive" argument, that is, a presentation of facts which are used, not to support a conclusion that may be true or false, but used to support a conclusion promoting a particular policy or course of action.

"Enough" is also a revealing book, a hard and detailed look at our rapid acceleration into technologies which may have permanent and adverse effects on the future of human beings; indeed, these technologies have the potential to affect what it means to be human at all. Because he perceives this to be a threatening situation, McKibben discusses technologies such as germline engineering and therapeutic cloning, warning that they represent a slippery slope that may make more dangerous and harmful technologies possible and even acceptable.

"[I]f we aggressively pursue any or all of several new technologies now before us," the author says, "we may alter our relationship not with the rest of nature but with ourselves. First human genetic engineering and then advanced forms of robotics and nanotechnology will call into question, often quite explicitly, our understanding of what it means to be a human being."

McKibben acquaints us with microscopic nanobots cruising our bloodstreams, attacking pathogens within our bodies and building new cells. And with children born so genetically enhanced that they will never be able to believe that they reached success as musicians or artists or athletes or whatever because there was something unique in them and a hunger to reach the pinnacle of their ability through their own choice and desire.

The author tackles what it means to be human, pointing out how these new technologies threaten our very identity as human beings. "What if we have been programmed," he asks, "or at least must suspect each time we choose a path that we have been nudged in that direction by our engineered cells? Who then 'are we'?"

One of the more interesting arguments that McKibben makes, in my opinion, has to do with the matter of "choice," an issue with which libertarians are always concerned. Libertarian-minded thinkers tend to be among the strongest advocates of modern technologies and tend to believe that the free market will police itself in regard to any dangers which may result from their use.

More often than not, libertarians accuse those who oppose or may merely question the effects of new technologies of being Luddites, a name attributed to that infamous group of early nineteenth century workers who protested against the introduction of new labor-saving technologies in the factories of that period.

But McKibben argues that some of these new biotechnologies are really "anti-choice." He points out that "In widespread use, they will first rob parents of their liberty, and then strip freedom from every generation that follows. In the end, they will destroy forever the very possibility of meaningful choice."

I think that's a point that needs to be thoughtfully and seriously considered, especially by those who are, like I am, more or less on the libertarian side of the socio-political spectrum.

McKibben is not a naive thinker. He realizes that there is no limit to human aspirations or desires. And our ability to discover new scientific facts and to invent new technologies seems unlimited. But can we draw a line and say this far and no further? Can we say, this is enough? The author answers yes, and argues that only by staying human can we find true meaning in our lives. What sets a human being apart from other beings in this world of ours? McKibben argues that it is our power of self-limitation. "We need to do an unlikely thing," he says. "We need to survey the world we now inhabit and proclaim it good. Good enough."

While allowing that many of these new technologies may hold the promise to cure disease and provide other benefits, they also offer problematic choices such as the capacity to choose a child's gender, the power to boost human intelligence and, what may be the nightmare of all nightmares, the option of "improving" or "perfecting" human beings. And, I have always argued and will continue to do so: just because we can do something does not mean it is something we should do or need to do. I find myself having to agree with McKibben when he concludes, "I think the stakes in this argument are absurdly high, nothing less than the meaning of being human. Must we forever grow in reach and power? Or can we, should we, ever say,'Enough'?" Maybe so, maybe in this case, maybe at this time.

This is a book that should be read by everyone who is concerned about the future of the human species.

Rating: 1 stars
Summary: Just another self-righteous, ignorant Luddite.
Review: Here we go again. Bill McKibben, who in his book "One" decided that if one child was good enough for him, then by golly, it was good enough for everyone else!, now writes a book on genetic engineering. Or, more accurately, makes a poor excuse for a book out of his fears, faulty premises, and jumped-to conclusions about genetic engineering.

...

McKibben, and ideological cohorts of his like the insufferably self-righteous Wendell Berry, are the left-wing equivalents of William Bennett. They're basically control freaks who think they know what's best for you. As long as the gullible, the guilty-minded, and the fanatical make a fetish out of the "natural," McKibben and his ilk will continue to spew and scribble apocalyptic tripe deploring the way most Americans prefer to live, work, enjoy, and, one day, re-engineer themselves....and make a handsome living at it.

Rating: 3 stars
Summary: Enough ..Misinformation about Genetic Reseaarch
Review: I had difficulty taking this book seriously. It seems as though the author has misinterpreted the findings of genetic research. As a result, he doesn't present the whole story. His fears are unfounded. Scientists know full well that life is not governed by genetic specifications. The psychological processes he discusses, such as music ability and intelligence, are influenced by many factors such as upbringing, life experiences, culture, cohort and education. Even in the late seventies, when I went to college, researchers accepted the premise that human traits ..especially psychological ones ..are brought about by the interaction of our genetic nature with our life experiences. Human development is a constant exchange between nature and the socializing influences of family and culture. To think that it is unilaterally determined by genetic makeup is fallacious.

Rating: 5 stars
Summary: Thought-Provoking
Review: So where to join the fray? I'll just say what I think, I guess. First of all, McKibben has written a highly informative and gripping book. He provides a good overview of some of the developments actually occurring in biotech, robotics, and nanotech right now (well, within the last few years), and then proceeds to outline his viewpoint of opposition to the radically transformative effects of these technologies. This is all well and good. Though I'm not sure how I come down on these issues, I greatly appreciated his viewpoint and thought that he had some compelling arguments against the use, or at least reckless use, of these technologies.

First of all, I do not think, as some other reviewers have stated, that his argument is Luddite or in any way antitechnological. He wholeheartedly agrees with, or at least supports, the efforts of biotech researchers, doctors, and roboticists to advance and apply their technologies in ways that do not radically alter the existential landscape. Where he gets nervous is when people start talking about modifying who we are on an extremely basic level. Try as one might, the discoveries of Galileo, Columbus, Einstein, and Bohr cannot be compared to germline engineering and nanotech. These were revelations of the external landscape, knowledge revolutions. The territory McKibben is trying to protect is the internal landscape.

Living to be 200 (or 500+), selecting from a catalog of gene upgrades for an unborn child, or becoming host to a swarm of nanomachines that act as immune system kevlar sounds pretty cool on paper, but his contention is that these technologies will ultimately dehumanize by making one of our last givens--our selves--into yet another commodity. Once committed to these technologies, we'll be locked in, forced to get the next upgrade every time there's a new advance (every few years?), forced to keep feeding the hungry corporate behemoths to keep ourselves tuned up. If not, we risk becoming obsolete and disconnected from the world we have allowed to come into being, not just economically or politically, as is the case with the disenfranchised now, but existentially, at our root level of being. If we don't get our kids genetic upgrades, they or their descendents will become second-, third-, or fourth-class human beings, forever relegated to the trashbin of history. And the poor may not even get the choice to procure gene upgrades or nanotech defenders, with the rich giving themselves a carte blanche to write their good fortune into the DNA of their descendants so that the advantages of "good blood" become literal.

Decide for yourselves whether this argument and his others are convincing, or whether the technologies he discusses are dangerous for some other reason. Nanotech and genefixing may make us so prosperous that everyone, all over the world, will become a golden god and begin living a life of ease. Perhaps history is not an accurate precedent when dealing with something so transformative. But even if you are a fervent supporter of gene manipulation or nanotech, you should read the book. Whether it's for the best or no, I do think McKibben is correct in saying that this is the only chance we have to say no. The genie in the bottle is making all sorts of promises, trying to get us to let her/him/it out, and though they may all come true, it will be nigh impossible to get that genie back in if things aren't to our liking.

McKibben wants us to say enough. I'm not quite convinced, but he has convinced me that we should step back, as a society, and look long and hard at this technology before we say OK to anything that is going to change who we are. I see nothing in our society to convince me that any of us have more than an extremely dim and immature understanding of who or what we are and are capable of right now, pre-germline engineering. Maybe we should spend some more time understanding ourselves before we pass judgment on "stupid," "limited" man and start trying to upgrade.

Rating: 4 stars
Summary: Good enough
Review: The book is a discussion of McKibben's opinions of genetic manipulation of humans, the history of stem cell and cloning research and the possible outcomes. It is not a scientific work, but succeeds as a discussion in bioethics.
The book would be very useful for those who are unfamiliar with the subject and those who are only beginning to study bioethics. Some of the information seems too superficial for me, since I am a Family Physician studying for a Master's in Bioethics. I still learned new information and am definitely informed by the author's viewpoint.
I disagree with some of his pessimism about the reaction of the subjects of genetic manipulation since all children have struggled with identity and we've done fairly well so far. However, Dr Leon Kass and other more informed minds agree with McKibben. (I wonder how much of our differing opinions and optimism/pessimism are due to *our* genetics and how much due to that very struggle? How much is nature, how much nurture and the specific portion of our environment that includes these discussions?)

Rating: 1 stars
Summary: Look out Galileo, Copernicus, Dr. Frankenstein, et al!
Review: The only thing new about this book is the author and the printing date. Its premise is as old as recorded history. "Man dare not venture into some areas or he risks waking the demon, being eaten by the sea monster, incurring the wrath of the gods, creating the Frankenstein monster, etc."

First of all, these dire predictions seldom (if ever) come to pass. Nuclear power is an excellent example. In spite of the dire warnings and gloomy scenarios, some how we've managed to avoid annihilation (I can hear the collective "well, not yet" issuing from the Naderites), much to the chagrin of doom-prophets like McKibben, I'm sure. We seem to manage to stay alive and even prosper whatever technologies we happen develop.

Most importantly, McKibben's proposal that we ban, cease, outlaw, restrict, move backwards, whatever, is untenable. You cannot stop people from eventually exploring these areas. The technologies will be developed. Pass all the laws you want. Set up all the inquisitions you can muster. Burn all the heretics you can round up. The Bible will still be translated into English. The printing press will still disseminate information to the masses. The world will still revolve around the sun, not vice versa. Even though God didn't give man wings he can still fly. The automobile will replace the horse. It will still be possible to exceed the speed of sound. Man will still be descended from lower life forms, and on and on.

McKibben challenges us to face the "fact" that things are as good as we need them to be. He asks us to imagine how life could actually be any better and believes that we must admit that we can't. Well, horse hockey! Ask someone at the end of the 19th century the same question and they would probably not be able to imagine the world we live in. They would probably have agreed with the statement, "Life can't get any better than it is right now." Point is we can't know what all this will mean for the future of mankind. I, for one, am not willing to abandon possibilities based on the fear mongering of a twenty-first century naysayer.

As for his argument that all this is somehow dehumanizing, nothing is more human than improving who we are and how we live. That is exactly how we've survived for the past 3.5 million years. Sorry Bill, but you can take your place with the old wives and leave the rest of us alone.

I'm glad McKibben has the ability to say what he says. He needs to thank technological advancement for the opportunity. Other wise, he'd still be plowing a field to put bread on the table instead of cashing a check and going to the store. This book is one of the best examples of cultural lag that I've seen lately. The sad thing is that so many agree with the premise out of ignorance and fear. But, that too has had it evolutionary advantages. Fortunately, it's always been the progressives that adapted and survived. Sorry Bill, I think you're headed for extinction.

Rating: 1 stars
Summary: Look out Galileo, Copernicus, Dr. Frankenstein, et al!
Review: The only thing new about this book is the author and the printing date. Its premise is as old as recorded history. "Man dare not venture into some areas or he risks waking the demon, being eaten by the sea monster, incurring the wrath of the gods, creating the Frankenstein monster, etc."

First of all, these dire predictions seldom (if ever) come to pass. Nuclear power is an excellent example. In spite of the dire warnings and gloomy scenarios, some how we've managed to avoid annihilation (I can hear the collective "well, not yet" issuing from the Naderites), much to the chagrin of doom-prophets like McKibben, I'm sure. We seem to manage to stay alive and even prosper whatever technologies we happen develop.

Most importantly, McKibben's proposal that we ban, cease, outlaw, restrict, move backwards, whatever, is untenable. You cannot stop people from eventually exploring these areas. The technologies will be developed. Pass all the laws you want. Set up all the inquisitions you can muster. Burn all the heretics you can round up. The Bible will still be translated into English. The printing press will still disseminate information to the masses. The world will still revolve around the sun, not vice versa. Even though God didn't give man wings he can still fly. The automobile will replace the horse. It will still be possible to exceed the speed of sound. Man will still be descended from lower life forms, and on and on.

McKibben challenges us to face the "fact" that things are as good as we need them to be. He asks us to imagine how life could actually be any better and believes that we must admit that we can't. Well, horse hockey! Ask someone at the end of the 19th century the same question and they would probably not be able to imagine the world we live in. They would probably have agreed with the statement, "Life can't get any better than it is right now." Point is we can't know what all this will mean for the future of mankind. I, for one, am not willing to abandon possibilities based on the fear mongering of a twenty-first century naysayer.

As for his argument that all this is somehow dehumanizing, nothing is more human than improving who we are and how we live. That is exactly how we've survived for the past 3.5 million years. Sorry Bill, but you can take your place with the old wives and leave the rest of us alone.

I'm glad McKibben has the ability to say what he says. He needs to thank technological advancement for the opportunity. Other wise, he'd still be plowing a field to put bread on the table instead of cashing a check and going to the store. This book is one of the best examples of cultural lag that I've seen lately. The sad thing is that so many agree with the premise out of ignorance and fear. But, that too has had it evolutionary advantages. Fortunately, it's always been the progressives that adapted and survived. Sorry Bill, I think you're headed for extinction.

Rating: 1 stars
Summary: Huh?
Review: This book has a goal: to scare you. That, in itself, doesn't make the book bad. While I am pro-biotech, I appreciate the fact that people are allowed to read and explore a myriad of positioins before they make up their mind. What bothers me, then, is that McKibben is so intent on scaring us into submission that he is either a.) puposely exaggerating and misunderstanding his information and doesn't care, or b.)literally doesn't know 'enough' about what he's writing so as not to notice his caricatures.

For instance - amd most troubleing -, well over 2/3rds of his citations are gotten from newspapers, trade magazines, and (a little better but not by a lot) popular science articles. So we get treated to all the exaggerated stories about the nutty little cult-like submovements that treat biotech as an unmitigated utopia while under the impression that this is the mainstream view. Well, the New York TImes is in the business of selling newspapers and reporting stories that can help them do it. If we haven't noticed, they are much less concerned with accuracy. But McKibben's index is not only littered with these types of exaggerated stories, but virtually all are gotten from the newspapers and trade rags. Not very professional.

Second (and partly due to the above) Mckibben is wont to grossly overexaggerate fears of genetic determinism. IF we can select genes for success, he says, then children will be comodities!!! But in saying this, he doesn't realisze - or doesn't let on - that a.) there is no gene combo for 'success' (such a blanket phrase), b.) success involeves quite a bit of 'luck' and evironment in addition to genetic factors; c.) a genetic tweek is by no means a gaurentee of superiority in a particular area. McKibben, though, doesn't know this; my guess becasue he is quoting from trade magazines that like to write article on the "gene for x" in order to give us a shocking and juicy cover story. "Beanbag genetics" is dead an someone forgot to tell McKibbon that he is more of a gentic determinist than even most genetic determinist are.

Third he writes aobut his fears that biotech will 'dehumanize' us. We get this alot and McKibben swears he is not a luddite. But the argument fits the bill perfectly: Limitations are what makes us human; the better humans are made to perform, the less human they'll be. McKibben says that we should just be happy with the progress we've made so far (after all, eradication of limitions in the past was a good thing; it is only the future doings that are problematic) and cash in our chips content only with the results gotten so far. But how would getting people to live longer, be less prone to obesity, have smarter brains, have better eye-sight, and have various other talnents be immoral? The problem is that McKibben doesn't really ARUGE a point here; he just repeats his emotional appeal about the joys of human limitaitons as they are (you too can die at 70! Woohoo!) like it doesn't require any further argument. But in light of all of the things we COULD be better at with biotech's help, we really deserve an explanation of why it is moral to know that you can improve humans and NOT do it.

Long and short: following McKibben's title, reading this book make me say: "Enough!"

Rating: 5 stars
Summary: Are we about to make ourselves obsolete? Read the book!
Review: This is one of the most thoughtful, and sobering, books I've ever read. McKibben takes a deep, serious and well-researched look at the implications of genetic engineering, nanotechnology, robotics and artificial intelligence, and the view is chilling. Whether you are a technophile or a technophobe, read this book. Some version of the post-human future McKibben envisions is racing toward us. Robert Adler, author of _Medical Firsts: From Hippocrates to the Human Genome_ and _Science Firsts: From the Creation of Science to the Science of Creation_.


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